IL-22 is a member of the IL-10 family of regulatory cytokines, which includes IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26.
Members of this family share partial homology in their amino acid sequences, but they are dissimilar in their biological functions.
Produced by T lymphocytes, IL-22 inhibits IL-4 production by Th2 cells, and induces acute phase reactants in the liver and pancreas.
IL-22 signals through a receptor system consisting of IL-10Rβ/CRF2-4 and IL-22R, both of which are members of the class II cytokine-receptor family.
The BioGems Human IL-22 Pre-Coated ELISA （Enzyme-Linked Immunosorbent Assay） kit is a solid phase immunoassay specially designed to measure IL-22 with a 96-well strip plate that is pre-coated with mouse monoclonal antibody specific for IL-22.
It contains E.coli-expressed recombinant IL-22.
The detection antibody is a biotinylated goat polyclonal antibody specific for IL-22.
The kit is analytically validated with ready to use reagents.
