IL-11 is a multifunctional cytokine produced by stromal cells, such as fibroblasts, epithelial cells and osteoclasts.
It is expressed in a wide variety of tissues, including thymus, lung, bone, connective tissue and central nervous system.
IL-11 plays an important regulatory role in hematopoiesis by stimulating growth of myeloid, erythroid and megakaryocyte progenitor cells.
It also regulates bone metabolism, inhibits production of proinflammatory cytokines, and protects against gastromucosal injury.
The BioGems Human IL-11 Pre-Coated ELISA （Enzyme-Linked Immunosorbent Assay） kit is a solid phase immunoassay specially designed to measure IL-11 with a 96-well strip plate that is pre-coated with mouse monoclonal antibody specific for IL-11.
It contains E.coli-expressed recombinant IL-11.
The detection antibody is a biotinylated goat polyclonal antibody specific for IL-11.
The kit is analytically validated with ready to use reagents.
