BCA-1/BLC, a CXC chemokine, is expressed in the liver, spleen, lymph nodes, appendix and stomach.
It exerts its activities through its only receptor, CXCR5.
BCA-1/BLC is a potent chemoattractant for B lymphocytes, and induces weak chemotactic response in T cells and macrophages.
It manifests no activity on neutrophils and monocytes.
The BioGems Human BCA-1 (CXCL13) Pre-Coated ELISA (Enzyme-Linked Immunosorbent Assay) kit is a solid phase immunoassay specially designed to measure BCA-1 (CXCL13) with a 96-well strip plate that is pre-coated with mouse monoclonal antibody specific for BCA-1 (CXCL13).
It contains E.coli-expressed recombinant BCA-1 (CXCL13).
The detection antibody is a biotinylated goat polyclonal antibody specific for BCA-1 (CXCL13).
The kit is analytically validated with ready to use reagents.