BAFF, a member of the TNF family of ligands, is expressed in T cells, macrophages, monocytes and dendritic cells.
BAFF is involved in stimulation of B and T cell function, and is an important survival and maturation factor for peripheral B cells.
BAFF signals through three different TNF receptors, TACI, BCMA and BAFF-R.
The BioGems Human BAFF Pre-Coated ELISA （Enzyme-Linked Immunosorbent Assay） kit is a solid phase immunoassay specially designed to measure BAFF with a 96-well strip plate that is pre-coated with mouse monoclonal antibody specific for BAFF.
It contains NSO-expressed recombinant BAFF.
The detection antibody is a biotinylated goat polyclonal antibody specific for BAFF.
The kit is analytically validated with ready to use reagents.
