84-7744-99　Anti-MouseCD62L (L-Selectin) Purified 100ug　04712-20-100

仕様

• サイズ：100ug
• The MEL-14 monoclonal antibody specifically reacts with L- selectin （CD62L）, a receptor with lectin-like and Epidermal Growth Factor-like domains.
• The weight of the CD62L molecules depend on their origin： 74 kDa （on lymphocytes） or 95 kDa （on neutrophils）.
• In the Mouseorganism, CD62L can be expressed by most thymocytes, on subsets of B and T lymphocytes, monocytes, eosinophils, and neutrophils.
• The L-selectin binds sulfated, fucosylated, and glycosylated glycoproteins （MadCAM-1, GLYCAM-1, and CD 34）.
• It mediates the migration of lymphocytes to the site of inflammation and their return to the peripheral lymphoid tissues and to the HEV （high endothelial venules）.
• In vitro, L-selectin inhibits this binding and the lymphocyte extravasation into peripheral lymph nodes.
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