84-7744-95　Anti-Mouse/Rat TNF-alpha SAFIRE Purified 50ug　84412-25-50

仕様

• サイズ：50ug
• The TN3-19 monoclonal antibody reacts with mouse and rat tumor-necrosis （TNF） alpha proteins.
• It is not cross-reactive with mouse TNF-Beta or human TNF.
• TNF-Alpha is a pleiotropic pro-inflammatory cytokine secreted by various cells, including adipocytes, activated monocytes, macrophages, B cells, T cells and fibroblasts.
• It belongs to the TNF family of ligands, and signals through two receptors, TNFR1 and TNFR2.
• TNF-α is cytotoxic to a wide variety of tumor cells, and is an essential factor in mediating the immune response against bacterial infections.
• TNF-α also plays a role in the induction of septic shock, autoimmune diseases, rheumatoid arthritis, inflammation, and diabetes.
• The TN3-19 antibody is reported to be a neutralizing antibody.
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