84-7744-08　Anti-Mouse MHC Class II (I-A/I-E) APC 25ug　86212-80-25

仕様

• サイズ：25ug
• The M5/114.15.2 monoclonal antibody or （M5/114） is specific for the mouse major histocompatibility complex class II, specific for the I-A and I-E subregion-encoded glycoproteins （alloantigens I-Ab, I-Ad, I-Aq, I-Ed, and I-Ek, but not the I-Af, I-Ak, nor I-As antigens）.
• The antibody also reacts with cells from the H-2p or H-2r haplotypes mice.
• The polymorphic determinant represented by the mouse major histocompatibility complex class II （MHC Class II） is expressed by the immune cells bearing the specified alloantigens, like T and B lymphocytes, monocytes, dendritic cells, and macrophages.
• The antibody doesn't react with the NOD H-2g7 haplotype alloantigens.
• M5/114 mAb inhibits I-A-restricted T cell responses of the Haplotypes H-2b, H-2d, H-2q, and H-2u.
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