84-7743-59　Anti-Mouse LPAM-1 Biotin 25ug　83212-30-25

仕様

• サイズ：25ug
• The DATK32 monoclonal antibody specifically reacts with an epitoPEof the Mouseα4β7 integrin （LPAM-1）.
• The two subunits of the LPAM-1 heterodimer are the 154 kDa α4 and the 130 kDa β7.
• Most mature lymphocytes, a subset of bone marrow cells, and some of the thymic cells express the α4β7 integrin heterodimer.
• α4β7 enhances the transendothelial migration of lymphocytes, and interacts with several ligands （fibronectin, CD106, and MAdCAM-1）.
• The interaction of DATK32 with the α4β7 induces the α4β7-dependent lymphocyte aggregation and inhibits LPAM-1-dediated cell adhesion.
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