84-7743-30　Anti-Mouse IL-13 SAFIRE Purified 50ug　83512-25-50

仕様

• サイズ：50ug
• The 1316H monoclonal antibody binds to mouse IL-13.
• IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and also by mast cells and NK cells.
• Targeted deletion of IL-13 in mice resulted in impaired Th2 cell development and indicated an important role for IL-13 in the expulsion of gastrointestinal parasites.
• IL-13 exerts anti-inflammatory effects on monocytes and macrophages and it inhibits the expression of inflammatory cytokines such as IL-1β, TNF-α, IL-6 and IL-8.
• IL-13 has also been shown to enhance B cell proliferation and to induce isotype switching, resulting in increased production of IgE.
• Blocking of IL-13 activity inhibits the pathophysiology of asthma.
• The 1316H antibody is reported to be a neutralizing antibody.
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