84-7742-97　Anti-Mouse Foxp3 PE 25 ug　83812-60-25

仕様

• サイズ：25 ug
• The MF23 monoclonal antibody specifically reacts with the mouse 50-55 kDa Foxp3 protein （JM2, IPEX）, a member of the forkhead family of transcription factors.
• Foxp3 is expressed by the Treg lymphocytes, whose development and function are influenced by the forkhead protein.
• Ectopic expression of Foxp3 in T lymphocytes inhibits their activity and cytokine expression.
• Mutations of Foxp3 result in the "scurfy" mice phenotype.
• It is reported that the MF23 antibody recognizes an epitope between 1-87 amino acids in the N-terminal domain of mouse Foxp3.
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