84-7741-99　Anti-Mouse CD86 (B7-2) FITC 500ug　08912-50-500

仕様

• サイズ：500ug
• The GL-1 monoclonal antibody reacts specifically with the mouse B7-2 （also known as CD86）, a costimulatory molecule expressed by B and T lymphocytes, macrophages （thioglycollate-induced from peritoneum）, astrocytes and dendritic cells.
• The memory CD4+ T lymphocytes express CD86 （as mRNA and protein）.
• CD86, and the B7-1 （CD 80） molecule, are ligands for CD152 and CD28, and influence the costimulatory interactions between lymphocytes B and T.
• B7-2 is also involved in the mouse natural killer cell-mediated cytotoxicity.
• The GL-1 antibody blocks the mixed lymphocyte reaction （MLR） and inhibits the T-cells stimulation by antigen-presenting cells.
• Mixtures of anti-B7-1 antibody and GL-1 were reported to inhibit the interaction between CD125 and its ligand with the in vivo priming of cytotoxic T lymphocytes.
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