84-7741-28　Anti-Mouse CD45.1 PE-Cyanine7 25 ug　07522-77-25

仕様

• サイズ：25 ug
• The A20 monoclonal antibody reacts with the leukocytes of the CD45.1-expressing mouse strains （DA, SJL/J, RIII, and STS/A）.
• It does not cross-react with cells that express CD45.2.
• The CD45 molecule is a member of the Protein Tyrosine Phosphatase （PTP） family, because its intracellular region contains two PTP domains.
• The extracellular region's variability is caused by different levels of glycosylation, and the splicing of the 4, 5, and 6 exons.
• The isoforms found in the mouse strains depend on the activation state, maturation stage and cell type, and are very important in B and T lymphocytes antigen receptor signal transduction.
• The A20 antibody inhibits some of the B lymphocytes responses, from CD45.1-expressing mice, to lipopolysaccharides and antigens.
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