84-7741-01　Anti-Mouse CD45 APC 25ug　07512-80-25

仕様

• サイズ：25ug
• The 30-F11 monoclonal antibody specifically reacts with all isoforms of CD45 and also with the alloantigens CD45.1 and CD45.2 （LCA）.
• CD45 is a transmembrane glycoprotein, expressed by all the hematopoietic cells, except for platelets and mature erythrocytes, which distinguishes the leukocytes from the non-hematopoietic cells.
• The CD45 molecule is a member of the Protein Tyrosine Phosphatase （PTP） family, because its intracellular region contains two PTP domains.
• The extracellular region's variability is caused by different levels of glycosylation, and the splicing of the 4, 5, and 6 exons.
• The isoforms found in the mouse strains depend on the activation state, maturation stage and cell type, and are very important in B and T lymphocytes antigen receptor signal transduction.
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