The 390 monoclonal antibody specifically reacts with mouse cd31, a 130-140 kDA type I transmembrane glycoprotein also known as platelet-endothelial cell adhesion molecule-1 (PECAM-1).
CD31 is reported to bind to CD38 and is expressed on platelets, monocytes, granulocytes, and endothelial cells.
It plays a role in angiogenesis, wound healing, cellular migration, and signal transduction.