84-7739-69　Anti-Mouse CD28 PE 50 ug　10312-60-50

仕様

• サイズ：50 ug
• The 37.51 monoclonal antibody specifically reacts with mouse CD28 molecule, a 45 kDa homodimer.
• It is expressed on most thymocytes, at low density on most of the CD4+ and CD8+ peripheral T lymphocytes, and on the natural killer cells.
• It is additionally found on activated splenocytes, mast cells, and thymocytes.
• CD 28 is a costimulator of T lymphocytes and a ligand for CD80 （B7-1）, and CD86 （B7-2）.
• The CD28 signaling stimulates the expression of IL-2 and IL-2 receptor and the cytotoxicity of CD3-activated T lymphocytes.
• The 37.51 antibody stimulates the proliferation of T lymphocytes and natural killer cells and their respective cytokine production.
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