84-7739-52　Anti-Mouse CD274 (PD-L1, B7-H1) PE 25ug　26812-60-25

仕様

• サイズ：25ug
• The 10F.9G2 monoclonal antibody specifically reacts with mouse CD274, also known as B7-H1 or PD-L1, a 43 kDa glycoprotein of the B7 family of the immunoglobulin superfamily.
• CD274 is expressed on the B and T lymphocytes, natural killer cells, and dendritic cells.
• The receptor for the B7-H1 molecule is PD-1, which contains an Immunoreceptor Tyrosine-based Inhibitory Motif （ITIM）, and is expressed on activated B and T cells.
• The interaction between CD274 and PD-1 seems to downregulate the T and B immune responses.
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