84-7738-52　Anti-Mouse CD152 (CTLA-4) PE 100ug　14612-60-100

仕様

• サイズ：100ug
• The UC10-4F10-11 monoclonal antibody specifically reacts with the mouse Cytotoxic T-Lymphocyte Antigen-4 （CTLA-4）, also known as CD152.
• It is a protein with a structure similar to CD28 regarding the genomic organization, amino acid sequence, and structure.
• CTLA-4 is expressed on activated T cells and CD25+/CD4+ Treg lymphocytes and binds the members of the B7 family, B7-1 （CD80） and B7-2 （CD86）, with higher affinity than CD28.
• CD28 seems to provide opposing signal to T lymphocytes, while CD152 inhibits the T lymphocytes progression to an activated state and their proliferation, CD28 is a costimulator.
• The mouse UC10 -4F10-11 monoclonal antibody does not cross-react with the rat leukocytes.
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