The APB5 monoclonal antibody specifically binds to the mouse CD140b molecule, otherwise known as the Platelet-Derived Growth Factor (PDGF) Receptor beta chain.
CD140b is a receptor tyrosine kinase expressed on embryonic tissue and adult mesenchymal-derived cells.
The APB5 antibody is reported to block the binding of PDGF-BB to the PDGF receptor.