84-7737-21　Anti-Human/Mouse CD44 SAFIRE Purified 500 ug　06511-25-500

仕様

• サイズ：500 ug
• The IM7 monoclonal antibody specifically reacts with all the isoforms and both alloantigens of the CD44 glycoprotein （Pgp-1, Ly-24）.
• CD44 is expressed on hematopoietic and non-hematopoietic cells, bone marrow myeloid cells, memory T lymphocytes, periphery activated B cells, CD4+ T lymphocytes, and CD8+ T lymphocytes.
• The periphery B and T lymphocytes upregulate the expression of CD44.
• CD44 binds to hyaluronan molecules, acting as an adhesion molecule.
• The IM7 antibody inhibits collagen-induced arthritis in DBA/1 mice, prevents central nervous system inflammation associated with experimental autoimmune encephalomyelitis, but exacerbates the experimental autoimmune thyroiditis in CBA/J mice.
• The IM7 antibody also cross-reacts with dog, human, pig, horse, cat, and cow leukocytes.
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