84-7736-69　Anti-Human TNF-alpha Purified 50 ug　84421-20-50

仕様

• サイズ：50 ug
• The MAb11 monoclonal antibody specifically reacts with human tumor necrosis factor alpha （TNF-alpha）, a 157 amino acid non-glycosylated protein.
• TNF-alpha is a pleiotropic pro-inflammatory cytokine secreted by various cells including adipocytes, activated monocytes, macrophages, B cells, T cells and fibroblasts.
• It belongs to the TNF family of ligands and signals through two receptors, TNFR1 and TNFR2.
• TNF-α is cytotoxic to a wide variety of tumor cells and is an essential factor in mediating the immune response against bacterial infections.
• TNF-alpha also plays a role in the induction of septic shock, auto immune diseases, rheumatoid arthritis, inflammation, and diabetes.
• The MAB11 antibody was generated from recombinant human TNF and is reported to be a neutralizing antibody.
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