84-7735-55　Anti-Human CD86 (B7-2) PE 25 tests　08911-60-25

仕様

• サイズ：25 tests
• The IT2.2 antibody reacts with human CD86, also known as B7-2, an 80 kDa cell surface protein which is a ligand for CD28, a co-stimulatory receptor for the T cell receptor （TCR）.
• CD28 can also bind a second B7 ligand known as CD80 （B7-1）.
• Both CD80 and CD86 are expressed on activated B cells and antigen-presenting cells.
• These ligands trigger CD28 signaling in concert with TCR activation to drive T cell proliferation, induce high-level expression of IL-2, impart resistance to apoptosis, and enhance T cell cytotoxicity.
• The interaction / co-stimulatory signaling between the B7 ligands and CD28 provides crucial communication between T cells and B cells or APCs to coordinate the adaptive immune response.
• The IT2.2 antibody may be used as a marker for CD86 expression on B cells, macrophages, and dendritic cells.
• It is reported to be cross-reactive with Rhesus, Cynomolgus and Common marmoset CD86.
• この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）