84-7734-06 Anti-Human CD40 PE-Cyanine7 100 tests 02511-77-100
仕様
- サイズ:100 tests
- The 5C3 monoclonal antibody specifically reacts with human CD40, a 48kDA type I glycoprotein.
- CD40 is part of the TNFR family and expressed on a subset of T cells, B cells, dendritic cells, and macrophages.
- It has been shown to be involved in the protection of B cells from apoptosis, B cell differentiation, co-stimulation, and isotype class-switching.
- The 5C3 antibody partially blocks the binding of CD40L (CD154).
- In the presence of IL-4 or PMA, the 5C3 antibody promotes B cell proliferation.
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