84-7731-99　Anti-Human CD253 (TRAIL) SAFIRE Purified 100ug　25611-25-100

仕様

• サイズ：100ug
• The RIK-2 monoclonal antibody recognizes human CD253, otherwise known as the TNF-related apoptosis inducing ligand （TRAIL） or tumor necrosis factor （ligand） superfamily member 10 （TNFSF10）.
• TRAIL is a cytotoxic protein, which activates rapid apoptosis in tumor cells, but not in normal cells.
• TRAIL-induced apoptosis is achieved through binding to two death-signaling receptors, DR4 and DR5.
• These receptors belong to the TNFR superfamily of transmembrane proteins, and contain a cytoplasmic "death domain", which activates the cell's apoptotic machinery.
• The RIK-2 antibody is reported to block cellular apoptosis induced by TRAIL.
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