The h209 monoclonal antibody reacts with human CD209, also known as Dendritic Cell-Specific Intercellular adhesion molecule 3 （ICAM-3）-Grabbing Nonintegrin （DC-SIGN）.
CD209 is a 44kDA type II membrane protein with a mannose-binding C-type lectin domain.
It is reported to bind ICAM-2, ICAM-3, Butyrophilin, and HIV-1 gp120.
CD209 is expressed on dendritic cells and is thought to mediate the endocytosis of pathogens, dendritic cell migration, and T cell proliferation.
