84-7730-64　Anti-Human CD152 (CTLA-4) PE 100 tests　14611-60-100

仕様

• サイズ：100 tests
• The BNI3 monoclonal antibody specifically reacts with human CD152, the Cytotoxic T-Lymphocyte Antigen 4 （CTLA-4）.
• CTLA-4 is expressed on activated CD28+ T cells, and binds the B7 family members B7-1 （CD80） and B7-2 （CD86）.
• The structure of CTLA-4 is similar to the structure of CD28, but the two molecules seem to have opposite roles on the T lymphocytes.
• CTLA-4 inhibits the progression of T cell activation, while CD28 stimulates it.
• This result explains the stimulating role that the immobilization of BNI3 plays on the T lymphocytes proliferation induced by CD28.
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