84-6253-88　［取扱停止］Dengue Virus Pan Serotype NS1 100ug　497128

特徴

• Dengue virus (DENV) is a single positive strand RNA virus of the Flaviviridae family and a causative agent of the infectious tropical disease Dengue fever.
• There are four serotypes of the virus, DENV-1, DENV-2, DENV-3 and DENV-4.
• Dengue NS1 (Non-Structural protein 1) is a versatile glycoprotein of the DENV that is secreted as a hexamer, binds to the cell surface, and has immune evasive functions.
• Dengue NS1 antigen is also used as an early detection marker (days 1 to 9 after onset) for dengue virus infection.
• Dengue fever is ranked by the World Health Organization (WHO) as the most critical mosquito-borne viral disease, globally.
• More than 40 percent of the world’s population, in more than 100 countries are at risk of dengue infection.
• The most significant dengue epidemics in recent years have occurred in Southeast Asia, the Americas and the Western Pacific.
• Each year, an estimated 390 million dengue infections occur around the world.
• Of these, 500,000 cases develop into dengue hemorrhagic fever – a more severe form of the disease, which results in up to 25,000 deaths annually.
• With more than one-third of the world’s population living in areas at risk of transmission, dengue infection is a leading cause of illness and death in the tropics and subtropics (WHO for Guidelines for Diagnosis, Treatment, Prevention & Control, 2009).
• As many as 100 million people are infected yearly.
• Dengue is caused by any one of four related viruses transmitted by mosquitoes.
• There are no vaccines available to prevent infection with dengue virus.
• Applications:Suitable for use in ELISA and Immunocytochemistry.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.