84-6252-78　CRIM1 100ug　583170

特徴

• CRIM1 (cysteine-rich motor neuron 1), a glycosylated type I transmembrane protein, plays a role in tissue development i.e.
• capillary formation and maintenance during angiogenesis.
• It contains an N-terminal IGF-binding protein-like motif and six von Willebrand-like cysteine-rich repeats (CRRs) in its extracellular domain.
• CRIM1 interacts with BMP4 and BMP7 via the CRRs and functions as an antagonist.
• CRIM1 is developmentally expressed in a number of tissues including the pancreas, kidney, placenta, brain and blood vessels.
• CRIM1 may participate in CNS and placental development by interacting with growth factors involved in motor neuron differentiation and survival.
• Applications:Suitable for use in ELISA, Immunofluorescence and Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1ug/mlImmunofluorescence: 20ug/mlOptimal dilutions to be determined by the researcher.
• Positive Control:Jurkat Cell Lysate, Jurkat Cell Slide
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.