Meckel syndrome (MKS) is an embryonic lethal, autosomal recessive disorder characterized by polycystic kidney disease, central nervous system defects, polydactyly and liver fibrosis.
B9D1 is a B9 domain-containing protein, one of several that are involved in ciliogenesis.
Alterations in expression of this gene have been found in a family with Meckel syndrome.
B9D1, and its related protein B9D2, form a complex with MKS1, disruption of which causes MKS.
B9D1 is thought to be required for normal hedgehog signaling, ciliogenesis, and ciliary protein localization.
Applications:Suitable for use in ELISA, Immunocytochemistry, Immunofluorescence and Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1ug/mlImmunocytochemistry: 5ug/mlImmunofluorescence: 20ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.02% sodium azide.
Specificity：Recognizes human B9D1. Wiill only recognize the longest isoform. B9D1 antibody is predicted to not cross-react with other DNAJC family members.
Isotype：IgG
Calc Applications Abbrev：E IC IF IHC
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to 18 amino acids, aa130-180, near the C-terminus of human B9D1. Species sequence homology: rat: (100%) and mouse: (100%)
