84-6252-21 Smad1 (Center) 200ul 378644
特徴
- Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase.
- SMAD1 is a receptor-regulated SMAD (R-SMAD) (By similarity).
- May play a role in the initiation and maintenance of spermatogenesis.
- SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1 (By similarity).
- May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene [removed]PubMed:15329343).
- Applications:Suitable for use in ELISA, Western Blot and Immunohistochemistry.
- Other applications not tested.
- Recommended Dilution:Western Blot: 1:1000Immunohistochemistry (paraffin): 1:25Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size：200ul
- Host：rabbit
- Source Antibody：mouse
- Grade：Affinity Purified
- Purity：Purified by Protein A and peptide affinity chromatography.
- Form：Supplied as a liquid in PBS, 0.09% sodium azide.
- Specificity：Recognizes human Smad1.
- Isotype：IgG
- Calc Applications Abbrev：E IHC WB
- Calc Crossreactivity：Hu
- Immunogen：KLH-conjugated synthetic peptide mapping to a fragment of residues within aa154-187 from mouse Smad1.
- Shelf Life：1year
- Swiss Prot Number：P70340
- EU Commodity Code：30021010
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