84-6249-46 ZRANB1 50ul 582509
特徴
- Specifically hydrolyzes 'Lys-29'-linked and 'Lys-33'-linked diubiquitin.
- Also cleaves 'Lys-63'-linked chains, but with 40-fold less efficiency compared to 'Lys-29'-linked ones.
- Positive regulator of the Wnt signaling pathway that deubiquitinates APC protein, a negative regulator of Wnt-mediated transcription.
- Plays a role in the regulation of cell morphology and cytoskeletal organization.
- Required in the stress fiber dynamics and cell migration.
- May also modulate TNF-alpha signaling.
- Applications:Suitable for use in ELISA, Western Blot and Immunohistochemistry.
- Other applications not tested.
- Recommended Dilution:Western Blot: 1:1000-1:5000Immunohistochemistry: 1:200-1:500Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size：50ul
- Host：rabbit
- Source Antibody：human
- Grade：Affinity Purified
- Purity：Purified by Protein G affinity chromatography.
- Form：Supplied as a liquid in 0.01M PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
- Specificity：Recognizes human ZRANB1.
- Isotype：IgG
- Calc Applications Abbrev：E IHC WB
- Calc Crossreactivity：Hu
- Immunogen：Recombinant protein corresponding to aa111-397 from human Ubiquitin thioesterase ZRANB1 protein.
- Shelf Life：1year
- Swiss Prot Number：Q9UGI0
- EU Commodity Code：30021010
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