Transcriptional coactivator of the p300/CBP-mediated transcription complex.
Activates transactivation through cAMP response element (CRE) sites.
Protects against cell death by inducing antiapoptotic and repressing pro-apoptotic transcripts.
Stimulates transcription from the estrogen-responsive or BCL-2 promoters.
Required for depolarization-induced transcription activation of the C-FOS promoter in neurons.
Associates with chromatin to the estrogen-responsive C3 promoter region.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry and Immunofluorescence.
Other applications not tested.
Recommended Dilution:Western Blot: 1:1000-1:5000Immunohistochemistry: 1:20-1:200Immunoflourescence: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein G affinity chromatography.
Form：Supplied as a liquid in 0.01M PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Specificity：Recognizes human TOX3. Species Crossreactivity: mouse
Isotype：IgG
Calc Applications Abbrev：E IF IHC WB
Calc Crossreactivity：Hu Mo
Immunogen：Recombinant protein corresponding to aa8-305 from human TOX high mobility group box family member 3 protein.
