84-6190-29 TNFRSF1A 50ul 579580
特徴
- Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha.
- The adapter molecule FADD recruits caspase-8 to the activated receptor.
- The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis.
- Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.
- Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry and Immunofluorescence.
- Other applications not tested.
- Recommended Dilutions:Western Blot: 1:1000-1:5000Immunohistochemistry (Paraffin): 1:200-1:500.
- Heat antigen retrieval is required using citrate buffer, pH 6.0
- Immunofluorescence: 1:50-1:200Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size：50ul
- Host：rabbit
- Source Antibody：human
- Grade：Affinity Purified
- Purity：Purified by Protein G affinity chromatography
- Form：Supplied as a liquid in PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol
- Specificity：Recognizes human TNFRSF1A.
- Isotype：IgG
- Calc Applications Abbrev：E IF IHC WB
- Calc Crossreactivity：Hu
- Immunogen：Recombinant protein corresponding to aa249-455 of human TNFRSF1A.
- Shelf Life：1year
- Swiss Prot Number：P19438
- EU Commodity Code：30021010
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