Binds to a retinoid X receptor (RXR) responsive element from the cellularretinol-binding protein II promoter (CRBPII-RXRE).
Inhibits the 9-cis-retinoicacid-dependent RXR alpha transcription activation of the retinoic acidresponsive element.
Active transcriptional corepressor of SMAD2.
Links thenodal signaling pathway to the bifurcation of the forebrain and the establishment of ventral midline structures.
May participate in the transmission of nuclear signals during development and in the adult, as illustrated by the downmodulation of the RXR alpha activities.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry and Immunofluorescence.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:5000Immunohistochemistry: 1:20-1:200Immunofluorescence: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein G affinity chromatography.
Form：Supplied as a liquid in 0.01M PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Specificity：Recognizes human TGIF1. Species Crossreactivity: mouse
Isotype：IgG
Calc Applications Abbrev：E IF IHC WB
Calc Crossreactivity：Hu Mo
Immunogen：Recombinant protein corresponding to aa8-375 from human homeobox protein TGIF1.
