Meiosis-specific telomere-associated protein involved in meiotic telomereclustering, also named bouquet formation, the telomere-mediated chromosomal movement along the nuclear envelope which is crucial for homologous pairing and synapsis.
Probably acts as a hub for the assembly of a conserved meiotic telomere complex required for chromosome movements via interaction with TERF1.
Promotes telomere association with the nuclear envelope and deposition of the SUN-KASH/LINC complex.
Also recruits cohesin to telomeres to develop structural rigidity.
Applications:Suitable for use in ELISA and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry: 1:20-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein G affinity chromatography.
Form：Supplied as a liquid in 0.01M PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Specificity：Recognizes human TERB1.
Isotype：IgG
Calc Applications Abbrev：E IHC
Calc Crossreactivity：Hu
Immunogen：Recombinant protein corresponding to aa301-550 from human Telomere repeats-binding bouquet formation protein 1.
