Component of the SOS system and an inhibitor of cell division.
Accumulation of SulA causes rapid cessation of cell division and the appearance of long, nonseptate filaments.
In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring.
This mechanism prevents the premature segregation of damaged DNA to daughter cells duringcell division.
The effect of overexpression of SulA is neutralized by antitoxinCbeA (yeeU) (PubMed:22515815).
Applications:Suitable for use in ELISA.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ug
Host：rabbit
Source Antibody：E. coli
Grade：Affinity Purified
Purity：Purified by Protein G affinity chromatography.
Form：Supplied as a liquid in 0.01M PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Specificity：Recognizes E. coli sulA.
Isotype：IgG
Calc Applications Abbrev：E
Calc Crossreactivity：Ec
Immunogen：Recombinant protein corresponding to aa1-169 from E. coli Cell division inhibitor SulA protein.
