Serine protease inhibitor, probably important for the anti-inflammatory and/or antimicrobial protection of mucous epithelia.
Contribute to the integrity and protective barrier function of the skin by regulating the activity of defense-activating and desquamation-involved proteases.
Inhibits KLK5, it's major target, in a pH-dependent manner.
Inhibits KLK7, KLK14 CASP14, and trypsin.
Applications:Suitable for use in ELISA and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry: 1:20-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein G affinity chromatography.
Form：Supplied as a liquid in 0.01M PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Specificity：Recognizes human SPINK5.
Isotype：IgG
Calc Applications Abbrev：E IHC
Calc Crossreactivity：Hu
Immunogen：Recombinant protein corresponding to aa722-847 from human serine protease inhibitor Kazal-type 5 protein.
