84-6140-41 SMAD1 50ug 577111
特徴
- Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase.
- SMAD1 is a receptor-regulated SMAD (R-SMAD).
- SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1.
- May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression.
- Applications:Suitable for use in ELISA, Immunohistochemistry and Immunofluorescence.
- Other applications not tested.
- Recommended Dilution:Immunohistochemistry: 1:20-1:200Immunoflourescence: 1:50-1:200Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size:50ug
- Host:rabbit
- Source Antibody:human
- Grade:Affinity Purified
- Purity:Purified by Protein G affinity chromatography.
- Form:Supplied as a liquid in 0.01M PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
- Specificity:Recognizes human SMAD1.
- Isotype:IgG
- Calc Applications Abbrev:E IF IHC
- Calc Crossreactivity:Hu
- Immunogen:Recombinant protein corresponding to aa150-250 from human Mothers against decapentaplegic homolog 1 protein.
- Shelf Life:1year
- Swiss Prot Number:Q15797
- EU Commodity Code:30021010
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