84-6120-13 SFN (Biotin) 50ug 576106
特徴
- Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways.
- Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif.
- Binding generally results in the modulation of the activity of the binding partner.
- When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway.
- May also regulate MDM2 autoubiquitination and degradation and thereby activate p53/TP53
- Applications:Suitable for use in ELISA.
- Other applications not tested.
- Recommended Dilution:Optimal dilutions to be determined by the researcher.
- Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
- For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
- Aliquots are stable at -20°C for 12 months after receipt.
- Dilute required amount only prior to immediate use.
- Further dilutions can be made in assay buffer.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size:50ug
- Host:rabbit
- Source Antibody:human
- Grade:Affinity Purified
- Purity:Purified by Protein G affinity chromatography.
- Form:Supplied as a liquid in 0.01M PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol. Labeled with Biotin.
- Specificity:Recognizes human SFN.
- Isotype:IgG
- Calc Applications Abbrev:E
- Calc Crossreactivity:Hu
- Immunogen:Recombinant protein corresponding to aa1-248 from human 14-3-3 protein sigma.
- Shelf Life:1year
- Swiss Prot Number:P31947
- EU Commodity Code:30021010
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