Cell surface receptor for PLXNA2 that plays an important role in cell-cell signaling.
Required for normal granule cell migration in the developing cerebellum.
Promotes reorganization of the actin cytoskeleton and plays an important role in axon guidance in the developing central nervous system.
Can act as repulsive axon guidance cue.
Has repulsive action towards migrating granular neurons.
May play a role in channeling sympathetic axons into the sympathetic chains and controlling the temporal sequence of sympathetic target innervation (By similarity).
Applications:Suitable for use in ELISA, Immunohistochemistry and Immunofluorescence.
Other applications not tested.
Recommended Dilution:Immunohistochemistry: 1:20-1:200Immunofluorescence: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:50ug
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by Protein G affinity chromatography.
Form:Supplied as a liquid in 0.01M PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Specificity:Recognizes human SEMA6A.
Isotype:IgG
Calc Applications Abbrev:E IF IHC
Calc Crossreactivity:Hu
Immunogen:Recombinant protein corresponding to aa755-990 from human Semaphorin-6A protein.