Has strong anti-HIV activity against T-tropic strains of HIV-1 and weaker activity against M-tropic strains of HIV-1.
Inhibits HIV-1 fusion and infection of CD4 LTR beta-gal cells in vitro.
Inhibits fusion of HIV infected CEM-SS cells with uninfected CEM-SS cells, and fusion of HIV-1 Env expressing HL2/3 cells with CD4 LTR beta-gal cells.
Binds to HIV gp120, HIV gp160 and to a lesser extent HIV gp41.
Binding to HIV gp120 is glycosylation dependent.
Binds with high specificity to the tetrasaccharide Man-alpha-1, 2-Man-alpha-1, 6-Man-alpha-1, 6- Man and also binds the higher-order oligosaccharides oligomannose 8 and oligomannose 9.
Does not bind to monosaccharides, complex or hybrid N-linked oligosaccharides or chitin.
Applications:Suitable for use in ELISA.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ug
Host:rabbit
Source Antibody:Scytonema varium
Grade:Affinity Purified
Purity:Purified by Protein G affinity chromatography.
Form:Supplied as a liquid in 0.01M PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.