Involved in countering the first line of host defense mechanisms.
Efficientlyinhibits opsonization, phagocytosis and killing of S.aureus by humanneutrophils.
Acts by binding and stabilizing human C3 convertases (C4b2a and C3bBb), leading to their inactivation.
The convertases are no longer able to cleave complement C3, therefore preventing further C3b deposition on the bacterial surface and phagocytosis of the bacterium.
Also prevents C5a-induced neutrophil responses.
Applications:Suitable for use in ELISA.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：Staphylococcus aureus
Grade：Affinity Purified
Purity：Purified by Protein G affinity chromatography.
Form：Supplied as a liquid in 0.01M PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Specificity：Recognizes Staphylococcus aureus scn.
Isotype：IgG
Calc Applications Abbrev：E
Immunogen：Recombinant protein corresponding to aa32-116 from staphylococcus aureus staphylococcal complement inhibitor protein.
