84-6087-06 RBPMS 50ug 574469
特徴
- Acts as a coactivator of transcriptional activity.
- Required to increaseTGFB1/Smad-mediated transactivation.
- Acts through SMAD2, SMAD3 andSMAD4 to increase transcriptional activity.
- Increases phosphorylation of SMAD2 and SMAD3 on their C-terminal SSXS motif, possibly through recruitment of TGFBR1.
- Promotes the nuclear accumulation of SMAD2, SMAD3 and SMAD4 proteins.
- Binds to poly(A) RNA.
- Applications:Suitable for use in ELISA and Immunohistochemistry.
- Other applications not tested.
- Recommended Dilution:Immunohistochemistry: 1:20-1:200Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size:50ug
- Host:rabbit
- Source Antibody:human
- Grade:Affinity Purified
- Purity:Purified by Protein G affinity chromatography.
- Form:Supplied as a liquid in 0.01M PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
- Specificity:Recognizes human RBPMS.
- Isotype:IgG
- Calc Applications Abbrev:E IHC
- Calc Crossreactivity:Hu
- Immunogen:Recombinant protein corresponding to aa1-219 from human RNA-binding protein with multiple splicing protein.
- Shelf Life:1year
- Swiss Prot Number:Q93062
- EU Commodity Code:30021010
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