84-6076-32 PYHIN1 100ug 573937
特徴
- Major mediator of the tumor suppressor activity of IFN in breast cancer cells.
- Promotes ubiquitination and subsequent degradation of MDM2, which leads to p53/TP53 stabilization.
- Promotes ubiquitination and subsequent degradation of HDAC1, which in turn enhances maspin expression, and impairs invasive activity of cancer cells.
- Applications:Suitable for use in ELISA and Western Blot.
- Other applications not tested.
- Recommended Dilution:Western Blot: 1:1000-1:5000Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size：100ug
- Host：rabbit
- Source Antibody：human
- Grade：Affinity Purified
- Purity：Purified by Protein G affinity chromatography.
- Form：Supplied as a liquid in 0.01M PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
- Specificity：Recognizes human PYHIN1.
- Isotype：IgG
- Calc Applications Abbrev：E WB
- Calc Crossreactivity：Hu
- Immunogen：Recombinant protein corresponding to aa1-245 from human Pyrin and HIN domain-containing protein 1 protein
- Shelf Life：1year
- Swiss Prot Number：Q6K0P9
- EU Commodity Code：30021010
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