RNA-binding protein that mediates pre-mRNA alternative splicing regulation.
Plays a role in the regulation of cell proliferation, differentiation and migration.
Positive regulator of EPO-dependent erythropoiesis.
Participates in cell differentiation regulation by repressing tissue-specific exons.
Promotes FAS exon 6 skipping.
Binds RNA, preferentially to both poly(G) and poly(U).
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry and Immunoprecipitation.
Other applications not tested.
Recommended Dilution:Western Blot: 1:1000-1:5000Immunohistochemistry: 1:20-1:200Immunoprecipitation: 1:200-1:2000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in 0.01M PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Specificity:Recognizes human PTBP3.
Isotype:IgG
Calc Applications Abbrev:E IHC IP WB
Calc Crossreactivity:Hu
Immunogen:Synthetic peptide corresponding to aa37-55 from human polypyrimidine tract-binding protein 3.