84-6063-64 Prf1 50ug 573310
特徴
- Plays a key role in secretory granule-dependent cell death, and in defenseagainst virus-infected or neoplastic cells.
- Plays an important role in killing other cells that are recognized as non-self by the immune system, e.g.
- in transplant rejection or some forms of autoimmune disease.
- Can insert into the membrane of target cells in its calcium-bound form, oligomerize and form large pores.
- Promotes cytolysis and apoptosis of target cells by facilitating the uptake of cytotoxic granzymes.
- Applications:Suitable for use in ELISA, Western Blot and Immunofluorescence.
- Other applications not tested.
- Recommended Dilution:Western Blot: 1:1000-1:5000Immunofluorescence: 1:50-1:200Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size:50ug
- Host:rabbit
- Source Antibody:mouse
- Grade:Affinity Purified
- Purity:Purified by Protein G affinity chromatography.
- Form:Supplied as a liquid in 0.01M PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
- Specificity:Recognizes mouse Prf1. Species Crossreactivity: human
- Isotype:IgG
- Calc Applications Abbrev:E IF WB
- Calc Crossreactivity:Hu Mo
- Immunogen:Recombinant protein corresponding to aa21-554 from mouse Perforin-1 protein.
- Shelf Life:1year
- Swiss Prot Number:P10820
- EU Commodity Code:30021010
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