The B regulatory subunit might modulate substrate selectivity and catalyticactivity, and also might direct the localization of the catalytic enzyme to aparticular subcellular compartment.
Within the PP2A holoenzyme complex,isoform 2 is required to promote proapoptotic activity (By similarity).
Isoform 2 regulates neuronal survival through the mitochondrial fission and fusion balance (By similarity).
Applications:Suitable for use in ELISA, Immunohistochemistry and Immunofluorescence.
Other applications not tested.
Recommended Dilution:Immunohistochemistry: 1:500-1:1000Immunofluorescence: 1:200-1:500Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein G affinity chromatography.
Form：Supplied as a liquid in 0.01M PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Specificity：Recognizes human PPP2R2B.
Isotype：IgG
Calc Applications Abbrev：E IF IHC
Calc Crossreactivity：Hu
Immunogen：Recombinant protein corresponding to aa1-200 from human serine/threonine-protein phosphatase 2A 55kD regulatory subunit B beta isoform protein.
