84-6059-52 PPP1R16B 50ug 573106
特徴
- Regulator of protein phosphatase 1 (PP1) that acts as a positive regulator of pulmonary endothelial cell (EC) barrier function.
- Involved in PKA-mediated moesin dephosphorylation which is important in EC barrier protection against thrombin stimulation.
- Promotes the interaction of PPP1CA with RPSA/LAMR1 and in turn facilitates the dephosphorylation of RPSA/LAMR1.
- Involved in the regulation of endothelial cell filopodia extension.
- May be a downstream target for TGF-beta1 signaling cascade in endothelial cells.
- Applications:Suitable for use in ELISA and Immunohistochemistry.
- Other applications not tested.
- Recommended Dilution:Immunohistochemistry: 1:20-1:200Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size：50ug
- Host：rabbit
- Source Antibody：human
- Grade：Affinity Purified
- Purity：Purified by Protein G affinity chromatography.
- Form：Supplied as a liquid in 0.01M PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
- Specificity：Recognizes human PPP1R16B.
- Isotype：IgG
- Calc Applications Abbrev：E IHC
- Calc Crossreactivity：Hu
- Immunogen：Recombinant protein corresponding to aa101-400 from human protein phosphatase 1 regulatory inhibitor subunit 16B protein.
- Shelf Life：1year
- Swiss Prot Number：Q96T49
- EU Commodity Code：30021010
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