Is preferentially associated with CBC-bound spliced mRNA-protein complexes during the pioneer round of mRNA translation.
Contributes to enhanced translational efficiency of spliced over nonspliced mRNAs.
Recruits activated ribosomal protein S6 kinase beta-1 I/RPS6KB1 to newly synthesized mRNA.
Involved in nuclear mRNA export; probably mediated by assoociation with the TREX complex.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunofluorescence and Immunoprecipitation.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:5000Immunohistochemistry: 1:20-1:200Immunofluorescence: 1:20-1:200Immunoprecipitation: 1:200-1:2000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ug
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by Protein G affinity chromatography.
Form:Supplied as a liquid in 0.01M PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Specificity:Recognizes human POLDIP3.
Isotype:IgG
Calc Applications Abbrev:E IF IHC IP WB
Calc Crossreactivity:Hu
Immunogen:Recombinant protein corresponding to aa100-221 from human polymerase delta-interacting protein 3.