84-6049-41 PLK2 100ug 572605
特徴
- Tumor suppressor serine/threonine-protein kinase involved in synaptic plasticity, centriole duplication and G1/S phase transition.
- Polo-like kinases act by binding and phosphorylating proteins are that already phosphorylated on a specific motif recognized by the POLO box domains.
- Phosphorylates CENPJ, NPM1, RAPGEF2, RASGRF1, SNCA, SIPA1L1 and SYNGAP1.
- Plays a key role in synaptic plasticity and memory by regulating the Ras and Rap protein signaling
- Applications:Suitable for use in Immunohistochemistry and ELISA.
- Other applications not tested.
- Recommended Dilution:Immunohistochemistry: 1:50-1:300ELISA: 1:5000-1:20,000Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size:100ug
- Host:rabbit
- Source Antibody:human
- Grade:Affinity Purified
- Purity:Purified by immunoaffinity chromatography.
- Form:Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
- Specificity:Recognizes human PLK2. Species Crossreactivity: rat
- Isotype:IgG
- Calc Applications Abbrev:E IHC
- Calc Crossreactivity:Hu Rt
- Immunogen:Synthetic peptide corresponding to aa1268-1341 from human PLK2.
- Shelf Life:1year
- Swiss Prot Number:Q9NYY3
- EU Commodity Code:30021010
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