Acts as a transcriptional activator of PF4 in complex with MEIS1.
Converted into a potent transcriptional activator by the (1;19) translocation.
May have a role in steroidogenesis and, subsequently, sexual development and differentiation.
Isoform PBX1b as part of a PDX1.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry and Immunofluorescence.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:5000Immunohistochemistry: 1:100-1:300Immunofluorescence: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:50ug
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by Protein G affinity chromatography.
Form:Supplied as a liquid in 0.01M PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Specificity:Recognizes human PBX1. Species Crossreactivity: rat
Isotype:IgG
Calc Applications Abbrev:E IF IHC WB
Calc Crossreactivity:Hu Rt
Immunogen:Recombinant protein corresponding to aa315-430 from human Pre-B-cell leukemia transcription factor 1 protein.